Permeation of Ions Across the Potassium Channel

Shin-ho H Chung
Protein Dynamics Unit, Faculty of Chemistry

Toby Allen
Protein Dynamics Unit, Faculty of Chemistry

Stuart Ramsden
ANU Supercomputer Facility

In April, 1998, the crystallographic structure of the potassium channel from the soil bacterium was unravelled by McKinnon and his colleagues.

McKinnon's WWW site

We present here some of the results our theoretical calculations that make use of the new structural information.

Additional information on these structures can be found here.

Part I. The Shape of the Channel

Part II. Molecular Dynamics Calculations

Part III. Electrostatic Calculations

Part IV. Brownian Dynamics Simulations

Researchers:

Shin-Ho Chung
Toby Allen
Matthew Hoyles
Serdar Kuyacak

Visualization:

Shin-Ho Chung
Toby Allen
Stuart Ramsden

The calculations upon which this work is based were carried out with the Fujitsu VPP-300 of the ANU Supercomputer Facility.

This work was supported by grants from the Australian Research Council and the National Health and Medical Research Council of Australia.


Last modified: Wed Jul 28 10:12:21 EST 1999